alexa Marek Malecki
ISSN: 2375-4508

Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology
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Marek Malecki

Dr. Marek Malecki, MD, PhD
Associate Professor of Genetics Genomics, and Gene Therapy
Western University of Health Sciences (WUHS)
Pomona, CA, USA
Biography

He earned MD degree at the Medical Academy, Poznan followed by Residency/Fellowship in Molecular Medicine in Rigshospitalet, Copenhagen. He earned PhD at the Polish Academy of Sciences, Warsaw followed by the postdoctoral fellowships in molecular biology at the Austrian Academy of Sciences, Salzburg, ETH, Zurich, Utrecht University, Utrecht, Cancer Center, Vienna, Cancer Center, Amsterdam, Biozentrum, Basel. He is currently Associate Professor of Genetics, Genomics, and Gene Therapy at the Western University, Pomona, CA and President of Phoenix Biomolecular Engineering Foundation, San Francisco, CA.

Marek Malecki MD PhD developed a cancer suicide gene therapy. It was initially developed for ovarian cancers as the means of targeted elimination of cancer cells, while retaining healthy cells intact. This is the best way to retain women’s fertility in cases of cancer. It is based upon the synthetic scFv and probes, which he invented and patented (USPTO and WIPO). A big role in this gene therapy is played by the nuclear routing network, which he discovered during his tenure at the NIH, National Biotechnology Resource. He also developed the unique protocols of cryo-immobilization of living cells which retain their high viability.

Research Interest

Cancer of ovaries, cancer of testes, cancer stem cells (CSC), circulating tumor cells (CTCs), genetic disorders, iatrogenic genetic mutations, gene therapy, targeted gene delivery, site specific recombination, fertility sparing therapy, biobanking, in vitro fertilization.

Publications

Novel Approach for Designing Supportive Care in Genetic Disorders of Gastrointestinal Tract: Three-Dimensional Polymer Model of Nutritional Therapies in Cystic Fibrosis, Ulcerative Colitis, and Crohn`s Disease

Paul Zarogoulidis, Ioannis Kioumis, Theodora Tsiouda, Nikolaos Pezirkianidis, Christos Ritzoulis, Haidong Huang, Wolfgang Hohenforst-Schmidt, Dionysios Spyratos, Konstantinos Porpodis, Georgia Pitsiou, Nikolaos Pezirkianidis, Sofia Lampaki, John Organtzis, Konstantinos Zarogoulidis, Bianca Malecki, Marek Malecki

Research Article: J Nanomedine Biotherapeutic Discov 2014, 4: 128

Suicide Gene Therapy for Cancer – Current Strategies

Paul Zarogoulidis, Kaid Darwiche, Antonios Sakkas, Lonny Yarmus, Haidong Huang, Qiang Li, Lutz Freitag, Konstantinos Zarogoulidis and Marek Malecki

Review Article: J Genet Syndr Gene Ther 2013, 4: 139

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