alexa Shyam Kottilil | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Shyam Kottilil

Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Biography

Shyam Kottilil is a Professor of Medicine at the Division of Clinical Care and Research at the Institute of Human Virology (IHV). He is also the Associate Chief of the Division of Clinical Care and Research and Co-director of the Clinical Trials Unit at the Institute. Prior to his appointment at IHV in 2014, Dr. Kottilil was at the Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases at the National Institutes of Health (Bethesda, USA). He received his MD from the Government Medical College (Trichur, India); he performed his residency in Internal Medicine at Brown University School of Medicine (Providence, RI, USA) and a fellowship in Infectious Diseases from the National Institute of Allergy and Infectious Diseases, NIH (Bethesda, USA). He received his Ph.D from Memorial University of Newfoundland (Canada), where he studied the role of cytotoxic cells in HIV infection. He joined the Immunopathogenesis Section of the NIAID, NIH (Bethesda, USA) in the year 2000, as a clinical fellow where he continues to study immunopathogenesis of Human Immunodeficiency virus and Hepatitis C viruses with Dr. Anthony S Fauci.

Research Interest

His current research objectives include: (1) design of novel therapeutic strategies to cure HCV and HBV (2) determination of clinical and biological correlates of anti-HCV and HBV treatment response; and (3) identification of biomarkers of disease progression, therapeutic response and tumorigenesis (hepatoma) using an integrated database approach (DNA, RNA, protein and function). In order to achieve the above goals, he conducts clinical trials employing Phase I, Phase II, and Phase III methodologies.

Publications

Sequential Therapy with Tenofovir Plus Peg Interferon Enhances Innate and Adaptive Immunity Compared to Tenofovir Monotherapy in Chronic Hepatitis B Patients

Nirupma Trehanpati, Arshi Khanam, Syed Hissar, Rashi Sehgal, Ritu Khosla, Paul David, Ashish kumar, Anupama Prashar, Ankit Bhardwaj, Shyam Kottilil and Shiv Kumar Sarin

Research Article: J Clin Cell Immunol 2014, 5: 272

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