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Journal of Research and Development

Journal of Research and Development
Open Access

ISSN: 2311-3278

+44-20-4587-4809

Thomas D Nolin

Thomas D Nolin

University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania, USA

Biography
Experienced pharmaceutical scientist with a demonstrated history of working in academia. Skilled in clinical and translational research, clinical pharmacology, quantitative analytical techniques, medical and pharmacy education, and life sciences. Long standing interest in the role of kidney function and the impact of kidney disease on pharmacokinetics, pharmacodynamics, corresponding drug selection and dosing requirements, and drug development practices and regulatory policies related to each. #nephropharmacology
Research Interest

Dr. Nolin's research interests include evaluation of the functional expression of drug metabolizing enzymes and transporters in humans, clinical pharmacokinetics in kidney disease, including assessment of PK during renal replacement therapy, and the development of novel analytical techniques. His primary research focuses on studying the impact of kidney disease on pathways of nonrenal drug clearance, particularly those mediated by cytochrome P450 enzymes and P-glycoprotein and organic anion transporting polypeptide transporters, as well as identifying mechanisms by which kidney disease contributes to alterations in these elimination pathways.

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