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Venkata Krishnan R was born in 1949 in Southern India. He graduated with M.Sc Med degree in Anatomy-Physiology from the University of Madras in 1972. In 1978 he was recipient of the DANIDA award to study neurophysiology at the Odense Universitet, Denmark; and in 1985 at the Australian National University, Canberra. As Assistant Professor he had taught anatomy and neuro-anatomy in medical schools in India, and later as Head of Department of Anatomy, at the Fiji School of Medicine (1982-1999). He received the physician diploma DHCP in 1996 from the University of the South Pacific. His published research since 1980 focuses on the locomotor learning activity-related plasticity of neuromuscular, spinal cord, and motor cortical synapses. Activity-dependent, competition-based selection of synaptic connections is a naturally-endowed process in these brain centres-now popularly known as synaptic competitive-learning (SCL). In 1991 he found that in spinal cord injury (SCI) paralysis SCL ceases to be operative. He further found that significant motor restoration can be achieved by re-installing SCL mechanisms in the injured cord networks, which he had verified in SCI animal models. These findings (2013-14) now pave the way for clinical trials in human SCI paralytics.
Locomotor learning activity-related plasticity of neuromuscular, spinal cord, and motor cortical synapses.
Letter to Editor: J Neurol Disord 2014, 2: 169