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This laboratory investigates cellular and molecular mechanisms of actions of anti-cancer agents with a long-term goal of developing novel strategies and effective agents for cancer therapy. We are particularly interested in the actions of two types of anti-cancer agents: metal binding compounds and n-3 polyunsaturated fatty acids. A combination of cellular, molecular, and biochemical approaches is applied to address critical questions in our in vitro and in vivo model systems.
We also investigate gene expression regulation in cancer cells, with our current effort focusing on microRNA regulation of gene expression.
Research Article: J Neurol Disord 2015, 3: 204
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