Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Bin Zhang
Cancer Hospital& institute, Chinese Academy of Medical Sciences, Peking Union Medical College,
No. 17 Panjiayuannanli, Chaoyang District, Beijing 100021
IR Iran
Research Article
Sentinel Lymph Node Biopsy in Papillary Thyroid Carcinoma
Author(s): Dan-Gui Yan, Bin Zhang, Lin Liu, Li-Juan Niu, Chang-Ming An, Zheng-Jiang Li, Zhen-Gang Xu and Ping-Zhang TangDan-Gui Yan, Bin Zhang, Lin Liu, Li-Juan Niu, Chang-Ming An, Zheng-Jiang Li, Zhen-Gang Xu and Ping-Zhang Tang
Background: The prognostic value of sentinel lymph node (SLN) biopsy mapping of tumor lymphatics for determining metastases in patients with papillary thyroid carcinoma (PTC) remains unconfirmed. Therefore, this study investigated the reliability and feasibility of the SLN biopsy to predict metastasis in PTC.
Methods: Fifty-one PTC patients without clinical evidence of lymph node involvement (cN0) underwent preoperative lymphoscintigraphy with Technetium-99m-labeled dextran. Total or near-total thyroidectomy was performed with SLN biopsy guided by intraoperative injection of methylene blue dye and scanning with a hand-held gamma probe. All patients received selective neck dissections.
Results: The SLN was identified by all three methods in all cases (100%). Identification rates for methylene blue dye and lymphoscin.. View More»
DOI:
10.4172/2167-7948.1000140