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IQGAP1 Mediates α-Smooth Muscle Actin Expression and Enhances Contractility of Lung Fibroblasts
Contractility is a predominant feature of myofibroblasts and a key process in fibrotic tissue remodeling. We previously demonstrated that lung fibroblasts from scleroderma patients with interstitial lung disease express a robust contractile phenotype and contain large amounts of the IQ motif containing GTPase activating protein (IQGAP1). Here we sh... Read More»
Akter T , Atanelishvili I , Shirai Y , Garcia-Martos A , Silver RM and Bogatkevich GS
: Rheumatology (Sunnyvale
10.4172/2161-1149.1000242Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article
