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Chad Jansen | OMICS International
ISSN 2476-1966

Journal of Immunobiology
Open Access

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Chad Jansen


Transcriptional and Functional Plasticity Induced by Chronic Insulin Exposure in a Mast Cell-Like Basophilic Leukemia Cell Model

Objective: Secretory granules (SG) and lipid bodies (LB) are the primary organelles that mediate functional responses in mast cells. SG contains histamine and matrix-active proteases, while LB are reservoirs of arachidonic acid and its metabolites, precursors for rapid synthesis of eicosanoids such as LTC4. Both of these compartments can be dynamic... Read More»

Chad Jansen, Mark Speck, William E Greineisen, Kristina Maaetoft-Udsen, Edward Cordasco, Lori MN Shimoda, Alexander J Stokes and Helen Turner

Research Article: J immuno Biol 2017, 2: 135

DOI: 10.4172/2476-1966.1000135

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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