Journal of Nutrition & Food Sciences
Open Access
ISSN: 2155-9600
ISSN: 2155-9600
Chao Kang
IR Iran
Review Article
Effect of Curcumin on IL-6 and IL-8: A Meta-analysis and Systematic Review
Author(s): Suocheng Hui, Kai Liu, Xiaohui Zhu, Chao Kang and Man-Tian MiSuocheng Hui, Kai Liu, Xiaohui Zhu, Chao Kang and Man-Tian Mi
Background and objectives: Studies that have investigated the effects of curcumin on the levels of IL-6 and IL-8 are controversial. We performed this meta-analysis to quantitatively evaluate the effects of curcumin on IL-6 and IL-8 regulation.Methods and study design: The PubMed, Embase, and Cochrane Library (updated to March 2017) databases were searched for related studies. The pooled effects of curcumin treatment on IL-6 and IL-8 were evaluated using a random-effects model. Nine studies comprising a total of 512 subjects were included in the current meta-analysis.Results: The overall outcome of this meta-analysis suggested that curcumin had no favorable effects on the concentration of IL-6 (-0.80 pg/mL; 95% CI, -1.61 to 0.01 pg/mL; P=0.052). Compared with control subjects, subjects treated with curcumin did not.. View More»
DOI:
10.4172/2155-9600.1000697