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Christian Barbato | OMICS International
ISSN: 2157-7099

Journal of Cytology & Histology
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Christian Barbato

Institute of Cell Biology and Neurobiology (IBCN), National Research Council (CNR), University Sapienza of Rome, Viale del Policlinico, 155, 00161 Rome

Dicer Silencing by siRNA in Cerebellar Granule Neurons

RNA-mediated gene silencing is a fundamental mechanism of gene expression regulation. A main component of RNA silencing machinery, the RNase III Dicer enzyme, catalyzes the processing of double-stranded RNAs (dsRNAs) into ≈21-25 nucleotide-long small interfering (si)RNAs and micro (mi)RNAs, an essential step in the biogenesis of small non-cod... Read More»

Christian Barbato

: J Cytol Histol 2019, 10. 539


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