Journal of Integrative Oncology

Corrado Pedrazzani

Publications

• Research Article
  A Novel Prognostic Score based on Serum Alpha-Fetoprotein, Number of Nodules, and MYC Gene Status Predicts Prognosis of Patients after Liver Resection for Hepatocellular Carcinoma
  Author(s): Andrea Ruzzenente, Fabio Bagante, Marco Sandri BS, Corrado Pedrazzani, Matteo Brunelli, Tommaso Campagnaro, Simone Conci, Paola Capelli, Alfredo Guglielmi, Aldo Scarpa and Calogero IaconoAndrea Ruzzenente, Fabio Bagante, Marco Sandri BS, Corrado Pedrazzani, Matteo Brunelli, Tommaso Campagnaro, Simone Conci, Paola Capelli, Alfredo Guglielmi, Aldo Scarpa and Calogero Iacono
  
  Recurrence after liver surgery for hepatocellular carcinoma (HCC) remains the major dismal event affecting patient’s overall survival (OS). Several studies on gene signature showed an association between MYC deregulation and poor prognosis. We aimed to analyze prognostic factors, including MYC status, for disease free survival (DFS) and OS, as well as to develop a new prognostic model for HCC able to predict the patient’s prognosis. Methods: Sixty-three patients who underwent liver resection for HCC from January 2006 to December 2009 in a single division of the Department of Surgery at the University of Verona were included into this study. Predictors of DFS and OS were identified using univariate and multivariate survival analysis. The prognostic ability of our model was compared using Harrell’s c-index to current clinical staging systems (AJCC/TNM 7th ed., BCLC and.. Read More»
  DOI: 10.4172/2329-6771.1000168

  Abstract PDF