Gynecology & Obstetrics
Open Access
ISSN: 2161-0932
ISSN: 2161-0932
David W Chan
IR Iran
Editorial
The Potential Molecular Therapeutic Approach in Targeting Ovarian Clear Cell Carcinoma
Author(s): David W Chan and Hextan YS NganDavid W Chan and Hextan YS Ngan
Ovarian Clear Cell Carcinoma (OCCC) is a distinctive subtype of Epithelial Ovarian Cancer (EOC). Compared with other subtypes of EOC, CCC has relatively poor in prognosis and bad outcome in current clinical management using maximal cytoreduction and platinum plus paclitaxel–based combined chemotherapy. Therefore, the investigation of molecular therapeutic approaches targeting at signaling pathways associated with chemoresistance is needed. This review describes some recent potential signaling pathway targets and also suggests putative small molecule kinase inhibitors as well as natural anti-cancer agents in combating this disease.
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DOI:
10.4172/2161-0932.1000e103