El Sharkawy A
Alexandria
Egypt
Research Article
Assessment of Urinary Netrin-1 as a Marker for Progression of Acute Kidney Injury in Critically Ill Patients: Prospective Cohort Study
Author(s): El Sharkawy A, El Wakil H, Naga Y and Younan DEl Sharkawy A, El Wakil H, Naga Y and Younan D
Background and objective: This study aimed to identify risk factors for progression of AKI in critically ill adult patients in the medical ICU in Alexandria main University Hospitals and to assess urinary netrin-1 as a marker for progression of AKI.
Design, setting, participants and measurements: The study included 80 AKI patients who were followed during their ICU stay for primary outcome (progression to severe AKI; KDIGO stage 2 or 3) and secondary outcomes (need for RRT, ICU mortality, length of ICU stay and SCr at the time of discharge from the ICU). All participants were subjected to history taking, full clinical examination and laboratory (routine and specific) investigations. Urine samples were collected for all patients at the time of ICU admission and urinary netrin-1 was measured.
Result: Almost one third (33.7.. View More»
