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Eric Altermann
Eric Altermann
Rumen Microbiology Team, AgResearch Limited, Grasslands Research Centre, Tennent Drive, Private Bag 11008, 4442 Palmerston North,
New Zealand
Publications
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Editorial
A Return to Microbial Genomes in the Metagenome Age
Author(s): Eric AltermannEric Altermann
Metagenomics has broadened significantly in microbial ecosystems, phylogenetic diversity and genetic complexity. In the course of only a few years microbial genomics has seen a dramatic rise from the 1.8 Megabase pair (Mbp) genome of the first free-living organism sequenced (Haemophilus influenzae Rd in 1995 [1]) to (meta) genome programmes now generating more than a Terabase pair of sequence data each. These advances have been made possible by increasingly more powerful sequencing technologies. Fluorescent slab-gel electrophoresis methods were replaced by capillary-based systems, which brought a significant increase in the level of throughput and automation. A step change came with the introduction of “sequencing by synthesis”. This technology was commercialised as ‘pyrosequencing’, notably by 454 Life Sciences. While initially providing only shorter read leng.. View More»
DOI: 10.4172/1948-5948.1000e111