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Gabriela Chiosis | OMICS International
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
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Gabriela Chiosis

Department of Molecular Pharmacology and Chemistry, Memorial Sloan-Kettering Cancer Centre, New York, NY, USA

Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention

Maintenance of cellular homeostasis is regulated by the molecular chaperones. Under pathogenic conditions, aberrant proteins are triaged by the chaperone network. These aberrant proteins, known as “clients,” have major roles in the pathogenesis of numerous neurological disorders, including tau in Alzheimer’s disease, α-synuc... Read More»

Aaron Carman, Sarah Kishinevsky, John Koren III, Wenjie Lou and Gabriela Chiosis

Review Article: J Alzheimers Dis Parkinsonism 2013, S10-007

DOI: 10.4172/2161-0460.S10-007

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article