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Hannah Elliott | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
Open Access

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Hannah Elliott

Australia
Publications

The Role of the Nef Protein in MHC-I Downregulation and Viral Immune Evasion by HIV-1

The Nef protein is a major determinant of pathogenicity caused by the Human Immunodeficiency virus (HIV) and is encoded by the nef gene within the genomes of primate lentiviruses HIV-1, HIV-2 and simian immunodeficiency virus (SIV). The HIV Nef protein subverts the intracellular membrane traffic to mediate endocytosis of a number of cell surface re... Read More»

Hannah Elliott and Gerard F Hoyne

Review Article: J Clin Cell Immunol 2015, 6: 375

DOI: 10.4172/2155-9899.1000375

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF

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