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Hengguang Li | OMICS International
ISSN: 2161-0444

Medicinal Chemistry
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Hengguang Li

Fayetteville, NC 28301

Synthesis of Cholic Acid-Peptide Conjugates With A Negatively Charged Ester Linkage for Oral Delivery

The progress in oral absorption of protein and peptide drugs has been hampered by the difficulty in transporting larger molecules across the gastrointestinal membrane. We are reporting here a study of the design and synthesis of cholic acid-peptide conjugates for peptide drug delivery through gastrointestinal track mediated by bile acid trans... Read More»

Hengguang Li, Haijing Song, Svein Oie and D’Robert Lu

Research Article: Med chem (Los Angeles) 2017, 7: 769

DOI: 10.4172/2161-0444.1000428

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article