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Hengyuan Zhang | OMICS International
ISSN: 2161-0444

Medicinal Chemistry
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Hengyuan Zhang

PR China

Synthesis and Biological Evaluation of Novel Furozan-Based Nitric Oxide-Releasing Derivatives of 23-Hydroxy Betulinic Acid and 3-oxo-23-hydroxybetulinic acid as Potential Anti-Tumor Agents

To search for novel nitric oxide (NO)-releasing anti-tumor agents, two series of furoxan-based NO-releasing derivatives of 23-Hydroxybetulinic acid and 3-oxo-23-hydroxybetulinic acid were designed and synthesized. The nitrate/nitrite levels in the cell lysates were assayed and the results showed that these derivatives could produce high levels of N... Read More»

Jie Liu, Fei Sun, Hengyuan Zhang, Hao Cai, Hequan Yao, Weijia Xie, Jieyun Jiang, Xiaoming Wu and Jinyi Xu

Research Article: Med Chem (Los Angeles) 2015, 5:028

DOI: 10.4172/2161-0444.1000239

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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