Pharmaceutical Regulatory Affairs: Open Access

Hideharu Shintani

Publications

• Review Article
  Current Mistaken Interpretation of Microbiological Data on Gas Plasma Sterilization
  Author(s): Hideharu ShintaniHideharu Shintani
  
  Even when using vegetative cells, a tailing phenomenon can be observed in survivor curves in engineering researcher’s papers on gas plasma sterilization. This indicates that even disinfection was not even achieved. By definition, sterilization is a process that kills all types of microorganisms including bacterial spores and vegetative cells. In contrast, disinfection kills only vegetative cells and does not kill bacterial spores. Tailing of a survivor curve is often caused by clumping of the biological indicator (BI), and engineering researchers who make their own BI without critical knowledge, appropriate techniques and confidential know-how to avoid such clumping frequently publish nonlinear survivor curves. Preparation of a monolayer of BI is quite a difficult task even for BI manufacturers and it requires proprietary information. Therefore, engineering researchers should pu.. Read More»
  DOI: 10.4172/2167-7689.1000138

  Abstract PDF