Journal of Blood Disorders & Transfusion

Himanshu Pathak

Publications

• Research Article
  Low Incidence of Clinically Significant Heparin Induced Thrombocytopenia after Cardiopulmonary Bypass Surgery
  Author(s): Abhinav B Chandra, Navneet Mittal, Shilpa Sambidi, Anuradha Belur, Swati Pathak, Himanshu Pathak and Yiqing XuAbhinav B Chandra, Navneet Mittal, Shilpa Sambidi, Anuradha Belur, Swati Pathak, Himanshu Pathak and Yiqing Xu
  
  Introduction: Thrombocytopenia after cardiopulmonary bypass (CPB) is common, and the diagnosis of heparin induced thrombocytopenia (HIT) remains a challenge in clinical practice despite the guidance from the “4T” diagnostic scoring criteria and the laboratory tests. Objectives: This study aims to evaluate (i) the temporal laboratory characteristics of thrombocytopenia after CPB and (ii) the incidence of clinically significant HIT based on clinical assessment. Methods: A retrospective data review of patients undergoing coronary artery bypass graft surgery or valve surgery who were also placed on bypass pump and received intra-operative heparin. Results: Among 450 study patients, 142 (31.5%) patients developed decrease of platelet counts at least 33% below base line following surgery, with a median degree of 61%. The initial platelet nadir occurred between day 0 to day 4 (me.. View More»
  DOI: 10.4172/2155-9864.1000180

  Abstract PDF