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Hiroyasu Akatsu | OMICS International
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

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Citations : 2275

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Hiroyasu Akatsu

Japan
Publications

Calpain-Mediated Hsp70.1 Cleavage in Monkey CA1 after Ischemia Induces Similar ‘Lysosomal Vesiculosis’ to Alzheimer Neurons

For the past decade evidence has gathered for the implication of lysosomes in the development of programmed cell death. Recent data advocate for dual roles of heat-shock protein 70.1 (Hsp70.1) not only as a molecular chaperone for damaged/aged proteins but also as a guardian of lysosomal integrity. Hsp70.1-mediated lysosomal stabilization is tightl... Read More»

Tetsumori Yamashima, Arumugam Mathivanan, Maryia Y. Dazortsava, Shota Sakai, Shota Kurimoto, Hong Zhu, Nozomi Funaki, Hanbai Liang, Françoise Hullin-Matsuda, Toshihide Kobayashi, Hiroyasu Akatsu, Hitoshi Takahashi and Yoshio Minabe

Research Article: J Alzheimers Dis Parkinsonism 2014, 4:139

DOI: 10.4172/2161-0460.1000139

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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