Lupus: Open Access
Open Access
ISSN: 2684-1630
+44 1300 500008
ISSN: 2684-1630
+44 1300 500008
Jamil M Allamani Ali
Malaysia
Research Article
Pediatric Systemic Lupus Erythematosus (SLE) Manifestations and Outcomes in a Tertiary Hospital
Author(s): Mohamad Ikram Ilias, Jamil M Allamani Ali, Nik Zainal Abidin Nik Ismail, Hans Van Rostenberghe and Azriani Ab RahmanMohamad Ikram Ilias, Jamil M Allamani Ali, Nik Zainal Abidin Nik Ismail, Hans Van Rostenberghe and Azriani Ab Rahman
Background: Systemic lupus erythematosus (SLE) is a relatively rare multisystemic autoimmune disorder in the pediatric age group. However, limited data regarding SLE among pediatric cohorts have been published. This retrospective study aimed to describe the sociodemographic influence, manifestation patterns, and outcomes of children with SLE in a 15-year period.
Methods: Fifty one children admitted to the Hospital Universiti Sains Malaysia between 1996 and 2010 were identified to manifest SLE on the basis of the international criteria established by the American College of Rheumatology.
Results: The median age of the children was 12 years. Females were predominantly affected; the male-to-female ratio was 1:10. A positive family history of autoimmune disorders was noted in 78% of the patients. Among the clinical manifesta.. View More»
DOI:
10.35248/2684-1630.17.2.123