Hereditary Genetics: Current Research

Jean Jacques Candelier

Publications

• Research Article
  Mature Cystic Ovarian Teratoma: A Study of 43 Congolese Cases
  Author(s): Henriette Poaty, Dimitry Moudiongui Mboungou, Yolande Voumbo Mavoungou, Jean Jacques Candelier, Jean Félix Peko, Léon Hervé Iloki and Philippe CoullinHenriette Poaty, Dimitry Moudiongui Mboungou, Yolande Voumbo Mavoungou, Jean Jacques Candelier, Jean Félix Peko, Léon Hervé Iloki and Philippe Coullin
  
  Background: The mature cystic ovarian teratoma (MCOT) is a common benign ovarian neoplasm in the world, most prevalent among women of childbearing age. It is a disease related to parental imprinting in which genome is exclusively maternal. The purpose of the study was to review the tumour features in Congolese patients in order to clarify its prevalence, and its histological forms and to report the eventual associated chromosomal anomalies described in literature. Methods: It was a retrospective study of MCOT seen in University Teaching Hospital of Brazzaville for a period of seven years, and five DNAs previously extracted from five MCOT. Two antibodies: DLK1 and TIMP2 were also studied by immunohistochemistry (IHC). The confirmed positive diagnosis was performed by Hematoxylin-Eosin method. The eventual presence of chromosomal anomalies.. View More»
  DOI: 10.4172/2161-1041.1000192

  Abstract PDF