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Lidia A. Gardner | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Lidia A. Gardner


Antibodies to the RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein A1 Colocalize to Stress Granules Resulting in Altered RNA and Protein Levels in a Model of Neurodegeneration in Multiple Sclerosis

Objective: Multiple sclerosis (MS) is the most common demyelinating disorder of the central nervous system (CNS). Data suggest that antibodies to CNS targets contribute to the pathogenesis of MS. MS patients produce autoantibodies to heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1). hnRNP A1 is an RNA binding protein (RBP) overexpressed in neu... Read More»

Joshua N. Douglas, Lidia A. Gardner, Hannah E Salapa and Michael C. Levin

Research Article: J Clin Cell Immunol 2016, 7: 402

DOI: 10.4172/2155-9899.1000402

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF