Angiology: Open Access
Open Access
ISSN: 2329-9495
+44 1478 350008
ISSN: 2329-9495
+44 1478 350008
Lingfeng Gao
Hainan medical College, No.3 Chengxi Xueyuan Road, Haikou, Hainan Special Economic Zone 571199
China
Research Article
The Aortic Windkessel Property Adaptation in Whole-body Immersion Stressed Mice
Author(s): Yang Wang, Annie Christel Bell, Han Wang, Boakye Kwabena, Shouyan Fan, Linghua Piao, Tong He, Zhibin Chen and Lingfeng GaoYang Wang, Annie Christel Bell, Han Wang, Boakye Kwabena, Shouyan Fan, Linghua Piao, Tong He, Zhibin Chen and Lingfeng Gao
Objective: Immersion induced hydrostatic pressure on thoracic cavity and limbs is one kind of cardiac overload model in simulating microgravity. We evaluated immersion hemodynamic parameters, investigated in vitro stretching induced aortic intact wall windkessel adaptations in whole-body immersion mice.Method: Kunming mice were divided into immersion group (n=20) and control group (n=10) randomize. In immersion group, mice further divided into immersion group (n=10) and immersion with weight-bearing group (5% of body weight, n=10). The immersion kept 20 min/day in warm water and continues for 1 week. The hemodynamic parameters were collected by left carotid artery cannulation and analyzed by biological signal acquisition system. Calculi of percussion wave were calculated with integral mode to determ.. View More»
DOI:
10.4172/2329-9495.1000222