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Lotte Engell-Noerregaard | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
Open Access

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Lotte Engell-Noerregaard


Influence of Metronomic Cyclophosphamide and Interleukine-2 alone or Combined on Blood Regulatory T Cells in Patients with Advanced Malignant Melanoma Treated with Dendritic Cell Vaccines

Background: Interleukine-2 and Cyclophosphamide are known to influence the circulating T cells and are used for immune manipulation in cancer patients. We analyzed the influence on the Treg population in three different dendritic cell (DC) vaccine trials including either concurrent interleukine-2 (IL-2), combined IL-2 and metronomic Cyclophosphamid... Read More»

Lotte Engell-Noerregaard, Eva Ellebaek, Trine Zeeberg Iversen, Troels Holz Hansen, Marie K Brimnes, Özcan Met, Jon Bjoern, Mads Hald Andersen, Per thor Straten and Inge Marie Svane

Research Article: J Clin Cell Immunol 2012, 3:118

DOI: 10.4172/2155-9899.1000118

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF