Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
+44 1300 500008
ISSN: 2155-9880
+44 1300 500008
Maravic-Stojkovic Vera
Dedinje Cardiovascular Institute,
M. Tepica 1, 11 000 Belgarde
Iran
Research Article
Changes in Interleukin-6 and Highly Sensitive C-Reactive Protein in Patients who Underwent Redo Coronary Artery Bypass Grafting
Author(s): Stojkovic Branislav, Vukovic Petar, Milojevic Predrag, Jovanovic Toma, Calija Branko, Maravic-Stojkovic Vera, Djukanovic Bosko and Jelena MarinkovicStojkovic Branislav, Vukovic Petar, Milojevic Predrag, Jovanovic Toma, Calija Branko, Maravic-Stojkovic Vera, Djukanovic Bosko and Jelena Marinkovic
Background: Determination of biomarkers can assess cardiac injury induced by cardiopulmonary bypass (CPB) during coronary artery bypass grafting (CABG). Open heart surgery initiates inflammatory reaction. Aim of this study was to compare the inflammatory response in patients undergoing first- and CABG-reoperation. Methods: Fifty-four patients (16% female, 84% male; 60.5 ± 6.5 vs. 66.2 ± 7.3 years) scheduled for elective cardiac surgery were divided into: Group 1, CABG primo-operation, and Group 2, CABG re-operation (redo CABG). The extent of inflammation was estimated by measuring interleukin (IL)-6 and highly sensitive C-reactive protein (hs- CRP) in plasma. Blood samples were collected: 24 hours prior, 6, and 24 hours after initiation of CPB. Demographic data, preoperative risk assessment Euro-score, laboratory values and clinical ou.. View More»
DOI:
10.4172/2155-9880.S7-003