Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
+44 1478 350008
ISSN: 2155-9554
+44 1478 350008
Massimiliano Scalvenzi
via Pansini 5, Naples, 80131,
Italy
Case Report
Blastic Plasmacytoid Dendritic Cell Neoplasm: Report Of A Case
Author(s): Massimiliano Scalvenzi, Lucia Gallo, Franco Palmisano, Massimo Mascolo, Orlando Zagaria and Gaetano De RosaMassimiliano Scalvenzi, Lucia Gallo, Franco Palmisano, Massimo Mascolo, Orlando Zagaria and Gaetano De Rosa
Blastic plasmacytoid dendritic cell neoplasm (BPDCN), also known as CD4+/CD56+ hematodermic neoplasm, is a rare, highly aggressive hematopoietic malignancy characterized by cutaneous, lymph node and bone marrow involvement, high risk of a leukemic dissemination, and a poor prognosis. It has been recognized as an independent entity in the World Health Organization (WHO) 2008 classification for cutaneous lymphomas and is thought to be derived from the precursors of plasmacytoid dendritic cells. This neoplasm most commonly affects middle-aged or elderly patients with predominant skin or soft tissue involvement. We report a case of a 87-year-old man with a purplered plaque on his face and multiple purple-red nodules on his trunk. Histopathology and immunohistological staining confirmed the diagnosis of blastic plasmacytoid dendritic cell neoplasm. .. View More»
DOI:
10.4172/2155-9554.S6-001