Advanced Techniques in Biology & Medicine
Open Access
ISSN: 2379-1764
ISSN: 2379-1764
Mauro Geller
Brazil
Research Article
Immunological Profile of Patients Presenting Down Syndrome and Alopecia Areata
Author(s): Marcia G Ribeiro, Juliany L Estefan, Kalynka Higino, Juan Clinton Llerena, Fernando R. Vargas, Suely Santos, Fabricio F. Costa, Marcelo P. Coutinho and Mauro GellerMarcia G Ribeiro, Juliany L Estefan, Kalynka Higino, Juan Clinton Llerena, Fernando R. Vargas, Suely Santos, Fabricio F. Costa, Marcelo P. Coutinho and Mauro Geller
Aim: This study was undertaken to contribute to knowledge of the immunological profile of Down syndrome and alopecia areata patients.
Material and Methods: Observational, case series study, with comparison group. The following data were computed: gender, age, karyotype, previous disease and immunological profile: complete blood count, Blood Sedimentation Rate (BSR), cellular and humoral immunity and autoimmunity. Frequency, central trends and dispersion measurements for descriptive analysis. The nonparametric χ2 test and Fisher Exact test for exploratory analyses; significance level for p value < 0.05.
Results: Eighty-three Down Syndrome (DS) patients were evaluated: 21 with Alopecia Areata (AA) and 62 without it. The average age of patients with AA was 13.3 years (SD ± 5.0) and of DS without AA was 12.2 (S.. View More»
DOI:
10.4172/2379-1764.1000123