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Mehdi Karoui | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Mehdi Karoui


Measurement of Indoleamine 2, 3 Dioxygenase Activity in Colorectal Cancer: A Controlled Group Study

Background: Indoleamine 2,3-dioxygenase (IDO), the rate-limiting enzyme that converts tryptophan (Trp) to kynurenine (Kyn), suppresses antitumor immune responses via depletion of Trp and accumulation of Kyn. We hypothesized that, in colorectal cancer (CRC), IDO activity may serve as a biomarker and thus we compared the IDO activity between patients... Read More»

Daniel Eyraud, Benjamin Granger, Noel Zahr, Frédéric Charlotte, Armelle Bardier, Gaëlle Gottrand, Audrey Perez-Lascar, Mehdi Karoui, Louis Lemoine, Jean Christophe Vaillant, David Klatzmann, Laurent Hannoun and Pierre Coriat

Research Article: J Clin Cell Immunol 2015, 6: 374

DOI: 10.4172/2155-9899.1000374

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF