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Michael Nolan
Michael Nolan
Tanzania
Publications
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Research Article
Anti-caries Potential of Silver Nanoparticles via Modulation of Free Calcium Activity within the Plaque Fluid of the Oral Biofilm: A Pilot Study
Author(s): Craig Callister, Matthew Callister, Michael Nolan and Ryan NolanCraig Callister, Matthew Callister, Michael Nolan and Ryan Nolan
Background: The specific aim of this study was to evaluate the effects of silver nanoparticles (AgNPs) on calcium ion activity within the plaque fluid of oral biofilms. Materials and Methods: An in ex-vivo prospective, randomized, controlled, double-blind study model was used. Two case study tests-one on a plaque from nine caries-free subjects (averaged samples) and another on a plaque from eight caries-free subjects (pooled samples) were done. All subjects abstained from brushing for 48 hours prior to the collection of plaque. All subjects were randomly assigned to a rinse which either contained calcium chloride (0.2% control), or calcium chloride (0.2%) and AgNPs (10 ppm). Plaque samples were taken prior to and 60 minutes after rinsing and spun down using a centrifuge and analyzed using calcium selective electrodes to determine ca.. View More»
DOI: 10.4172/2161-1122.1000529