Anatomy & Physiology: Current Research
Open Access
ISSN: 2161-0940
+44 1300 500008
ISSN: 2161-0940
+44 1300 500008
Miguel Alsina Casanova
Institut de Recerca Pediàtrica, Hospital Sant Joan de Déu,
Spain
Research Article
Multiorgan Dysfunction in Infants of 33-35 Weeks Gestation with Severe Hypoxic-Ischemic Encephalopathy Treated with Hypothermia
Author(s): Miguel Alsina Casanova, Ana Martín Ancel, Marisol León Lozano, Gemma Arca Díaz, Elia Pérez Fernández and Alfredo García AlixMiguel Alsina Casanova, Ana Martín Ancel, Marisol León Lozano, Gemma Arca Díaz, Elia Pérez Fernández and Alfredo García Alix
Background: The benefits of hypothermia on neurodevelopment of newborns ≥ 36 weeks gestation with hypoxicischemic encephalopathy have been shown in large clinical trials. The security of hypothermia in premature infants ≤ 36 weeks has not been rigorously evaluated, although its feasibility has been suggested in recent studies. The present study aims: 1) To describe extraneural involvement in infants 33-35 weeks gestation with severe hypoxicischemic encephalopathy treated with hypothermia 2) To compare organ dysfunction with infants ≥ 36 weeks gestation.
Methods: Retrospective observational study of prospective data collected. Consecutive newborns of 33-35 weeks gestation, ≥ 1800g birth weight and severe hypoxic-ischemic encephalopathy were included. Data were compared with a cohort of newborn infants ≥ 36 weeks with severe enc.. View More»
DOI:
10.4172/2161-0940.1000305