Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Mitsuru Nakazawa
Hirosaki University Graduate School of Medicine,
Hirosaki
Japan
Review Article
Oxidative Stress in the Vitreous Fluid with Rhegmatogenous Retinal Detachment
Author(s): Yukihiko Suzuki, Kobu Adachi, Shizuka Takahashi, Atsuko Maeno and Mitsuru NakazawaYukihiko Suzuki, Kobu Adachi, Shizuka Takahashi, Atsuko Maeno and Mitsuru Nakazawa
Purpose: To characterize the biological antioxidant potential (BAP) in the vitreous fluid in patients with rhegmatogenous retinal detachment (RRD).
Design: Laboratory investigation.
Materials and methods: Undiluted vitreous fluid was obtained at the time of vitrectomy from patients with RRD (45 eyes), proliferative diabetic retinopathy (PDR, 93 eyes), retinal vein occlusion (14 eyes), epiretinal membrane (ERM, 18 eyes) and macular hole (MH, 24 eyes). The BAP values were determined by measuring the reducing potential shown by the conversion of Fe3+ to Fe2+. Clinical features including the extent of the detachment, duration of symptoms, presence of proliferative vitreoretinopathy or vitreous hemorrhaging, and macular status (on or off), as well as the patient age were analyzed.
Results: RRD.. View More»
DOI:
10.4172/2155-9570.1000682