Journal of Blood Disorders & Transfusion

Mohamad Javad Zahedi

Publications

• Research Article
  Frequency of Anti-HBc & HBV DNA detection in blood donors of Kerman province, Iran
  Author(s): Maryam Delavari, Naser Shahabi-Nejad, Andre M.N. Renzaho, Mohamad Javad Zahedi and Amin Reza OwhadiMaryam Delavari, Naser Shahabi-Nejad, Andre M.N. Renzaho, Mohamad Javad Zahedi and Amin Reza Owhadi
  
  Hepatitis B is a serious global infection disease and a major cause of mortality and morbidity worldwide. However, data on Occult Hepatitis B in Iran are scare. The current study assessed the frequency of Anti-HBc and HBV DNA in serum sample of healthy blood donors negative for HBsAg stratified by sex and age; and also investigated the relationship between detection of HBV-DNA and anti-HBc positivity. Since anti-HBc screening is not performed in Iranian Blood Bank, we assessed whether anti-HBc could be adopted as a screening assay for the donated blood. The study included a total of 1525 blood samples of blood donors negative for hepatitis B virus surface antigen ( 87% male with a mean age ± SD: of 31±8yr; and 13% female with a mean age ± SD of 30±6yr). Eight percent (121 out of 1525) of the blood samples with negative HBs-Ag were positive for Anti-HBc and .. View More»
  DOI: 10.4172/2155-9864.1000105

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