Journal of Stem Cell Research & Therapy

Morayma Reyes

Publications

• Research Article
  Purification, Expansion and Characterization of Putative Murine Cardiac Progenitor Cells
  Author(s): Kanit Reesukumal, Busadee Pratumvinit, Marianna Rudakova, Kajohnkiart Janebodin and Morayma ReyesKanit Reesukumal, Busadee Pratumvinit, Marianna Rudakova, Kajohnkiart Janebodin and Morayma Reyes
  
  Ischemic heart disease kills more people than any other condition. Medical treatment for ischemic heart disease is currently limited by the heart’s lack of regeneration after injury. Recent reports have suggested the existence of cardiac progenitor cells in the adult normal and diseased mammalian heart. The origin of these cells is unclear. We implemented novel culturing conditions to isolate putative cardiac progenitor cells (pCPCs) from the adult murine heart atrium with the properties of cardiac regeneration. Putative adult cardiac progenitor cells were purified and expanded from adult murine hearts by expansion medium supplemented with 2% fetal calf serum, epidermal growth factor, platelet-derived growth factor and leukemia inhibitory factor. Under the culture condition of 5% O2 , these cells can be expanded beyond 42 days, expressed stem cell antigen (Sca-1) and card.. View More»
  DOI: 10.4172/2157-7633.S1-002

  Abstract PDF