Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Muhammad Mujammami
Jewish General Hospital,
3755 Cote Ste Catherine Montreal, Quebec, H3T-1E2
Canada
Case Report
Metachronous Collision Tumors of the Thyroid Gland Unveiled in Real Time by a Change in the Thyroid Nodule Phenotype
Author(s): Muhammad Mujammami, Louise Rochon, Stephan Probst, Richard Payne and Michael TamiliaMuhammad Mujammami, Louise Rochon, Stephan Probst, Richard Payne and Michael Tamilia
Introduction: The term collision tumor refers to the coexistence of two histologically distinct neoplastic tumors within the same mass. Collision tumor of the thyroid (also referred to as tumor-to-tumor metastasis) with metastatic colorectal carcinoma to a preexisting thyroid adenomatoid nodule is rare. Preoperative diagnosis of this disorder is exceedingly difficult. This report highlights the rare occurrence of a tumor-to-tumor metastasis of colorectal cancer to a preexisting thyroid adenomatoid nodule unveiled in real time by serial positron emission tomography CT scans (PET/CT). Since cytological diagnosis of these lesions is often insufficient, we present a stepwise diagnostic approach with a combination of investigations in the preoperative setting. The patient management is reviewed together with a rationalized use of targeted therapy based on the genetic statu.. View More»
DOI:
10.4172/2167-7948.1000180