Nathalie Bardin
Laboratoire d’Immunologie, UFR Pharmacie, Aix-Marseille Université,
UMRS1076, Marseille
France
Review Article
Antiphosphatidylethanolamine Antibodies: New Pieces to the Puzzle of the Antiphospholipid Syndrome?
Author(s): Caroline Zaratzian, Joris Zypinoglou, Pierre Emmanuel Morange and Nathalie BardinCaroline Zaratzian, Joris Zypinoglou, Pierre Emmanuel Morange and Nathalie Bardin
Objective: To show the contribution of antiphosphatidylethanolamine antibodies (aPE) screening in Antiphospholipid antibody syndrome (APS) diagnosis, especially in Antiphosphopholipid Syndrome (SNAPS) patients, based on litterature data.
Methods: A comprehensive literature review of English-language articles from January 1st 2000 to December 31th 2014 was performed using PudMed. Keywords used for the search were: seronegative antiphospholipid antibody OR phosphatidylethanolamine function, biosynthesis and physiological roles OR antiphosphatidylethanolamine antibody OR seronegative antiphospholipid syndrome.
Results: Although aPE was not included in the Sapporo criteria for the classification of APS, many studies described a significant association between aPE and the main clinical events of AP.. View More»
