Nelly H. Ali Eldin
Egypt
Research Article
Measles, Mumps, Varicella Zoster, Diphtheria and Hepatitis B Surface Antibody Status in Pediatric Acute Leukemic Patients
Author(s): Hanaa M Alam El-Din, Samah Aly Loutfy, Hany Abdel-Rahman, Nelly H. Ali Eldin, Hanan Ali Ahmed Madani and Mohamed SedkyHanaa M Alam El-Din, Samah Aly Loutfy, Hany Abdel-Rahman, Nelly H. Ali Eldin, Hanan Ali Ahmed Madani and Mohamed Sedky
Background and Aim: This is a preliminary study to evaluate the levels of protective antibodies against some of the vaccine preventable diseases, as a part of the nationwide vaccination program, in Acute Lymphocytic Leukemic children (ALL) and in their non cancer controls of matched age and sex.
Methods: Serum antibody levels of measles, mumps, Varicella zoster, diphtheria, and hepatitis B surface antigen were evaluated by ELISA technique in 120 children with ALL as well as in 60 children with no malignancy as a control group.
Results: A protective serum antibody level to measles, mumps, Varicella zoster, diphtheria and hepatitis B were detected in 53%, 14%, 38%, 83% and 72%, respectively of leukemic children irrelevant to phase of treatment compared to 53%, 20%, 40%, 75% and 67%, in the controls. Seropositivity ra.. View More»
DOI:
10.4172/2155-9864.S1-008