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Nicole Parker | OMICS International
ISSN: 2161-105X

Journal of Pulmonary & Respiratory Medicine
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Nicole Parker


Mice Lacking Epithelial I-?B Kinase are Protected from Lipopolysaccharide and Cigarette Smoke Extract Induced Inflammation

Background: IKK-2 activity is essential for cytokine mediated NFκB activation and subsequent expression of a wide variety of inflammatory genes. To investigate the role of IKK-2 signalling in lung epithelium we have developed a knock out mouse in which we have specifically deleted the IKK-2 gene in lung epithelial cells. Materials and Method... Read More»

David Lamb, Nicole Parker, Kristina Ulrich, Gareth Jones, Coralie Afeldorfer, Manolis Pasparakis, Steven Evans and Iain Kilty

Research Article: J Pulm Respir Med 2013, 3: 142

DOI: 10.4172/2161-105X.1000142

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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