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Nigel J Temperton | OMICS International
ISSN: 1747-0862

Journal of Molecular and Genetic Medicine
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Nigel J Temperton


The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes

The monomer of influenza haemagglutinin is synthesized as a single polypeptide precursor that during maturation is cleaved by proteases into two active subunits. Other studies have demonstrated that the human Transmembrane Protease Serine 2 (TMPRSS2) can cleave the HA of human seasonal influenza viruses. Consequently, we have investigated the use o... Read More»

Francesca Ferrara, Eleonora Molesti, Eva Böttcher-Friebertshäuser, Giovanni Cattoli, Davide Corti, Simon D Scott and Nigel J Temperton

Research Article: J Mol Genet Med 2013, 7:55

DOI: 10.4172/1747-0862.1000055

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF