Transplantation Technologies & Research

Phuong-Thu Pham

Publications

• Editorial
  BK Virus Screening and Management Following Kidney Transplantation: An Update
  Author(s): Phuong-Thu Pham, Joanna Schaenman and Phuong-Chi PhamPhuong-Thu Pham, Joanna Schaenman and Phuong-Chi Pham
  
  BK virus is a ubiquitous human virus with a peak incidence of primary infection in children 2-5 years of age and a seroprevalence rate of greater than 60-90% among the adult population worldwide. Following primary infection, BK virus preferentially establishes latency within the genitourinary tract and frequently reactivates in the setting of immunosuppression. In renal transplant recipients, BK virus is associated with a range of clinical syndromes including asymptomatic viruria with or without viremia, ureteral stenosis and obstruction, interstitial nephritis, and BK allograft nephropathy (BKN). BKN most commonly presents with an asymptomatic rise in serum creatinine between 2 to 60 months after engraftment (median 9 months). A definitive diagnosis requires an allograft biopsy. Over the last two decades, BKN has been recognized as an important cause of allograft dysfunction and graf.. Read More»
  DOI: 10.4172/2161-0991.1000e119

  Abstract PDF