Veterinary Science & Technology

Ramesh Gupta C

Publications

• Research Article
  Evaluation of Terminalia chebula Extract for Anti-Arthritic Efficacy and Safety in Osteoarthritic Dogs
  Author(s): Nichole Murdock, Ramesh Gupta C, Natalia Vega, Katie Kotora, Jean Miller, John Goad T, Michelle Lasher A, Terry Canerdy D and Sanyasi R KalidindiNichole Murdock, Ramesh Gupta C, Natalia Vega, Katie Kotora, Jean Miller, John Goad T, Michelle Lasher A, Terry Canerdy D and Sanyasi R Kalidindi
  
  The present investigation was undertaken to assess anti-inflammatory and anti-arthritic efficacy and safety of T. chebula extract (TCE) in moderately osteoarthritic (OA) dogs. Dogs with OA received either 500 mg placebo or 500 mg TCE twice daily for 150 days. On a monthly basis, dogs were given a full physical exam and were evaluated for arthritic pain (overall pain, pain upon limb manipulation, and pain after physical exertion), inflammation (erythrocyte sedimentation rate, ESR), and analysis of complete blood count (CBC) and serum biomarkers of liver (bilirubin, ALT, and AST), kidney (BUN and creatinine), and heart and skeletal muscle (CK) functions. Elbow and stifle joints were radiographed on day 0 and day 150 for evaluation of arthritic progression. Dogs given TCE showed significant (P<0.01) reductions in overall pain, pain upon limb manipulation, and pain after physical exert.. Read More»
  DOI: 10.4172/2157-7579.1000290

  Abstract PDF