Bioceramics Development and Applications

Sampath Kumar TS

Publications

• Research Article
  Silver and Gadolinium Ions Co-substituted Hydroxyapatite Nanoparticles as Bimodal Contrast Agent for Medical Imaging
  Author(s): Madhumathi K, Sampath Kumar TS, Mohammed Sanjeed T, Sabik Muhammed A, Sahal Nazrudeen and Sharanya DMadhumathi K, Sampath Kumar TS, Mohammed Sanjeed T, Sabik Muhammed A, Sahal Nazrudeen and Sharanya D
  
  Developing multimodal contrast agents is an upcoming area and hydroxyapatite nanoparticles substituted with various elements like gadolinium, eurobium etc., seems to be a promising contrast agent, especially for multimodal imaging of bone-tissue interface. A bimodal contrast agent using silver (Ag+) and gadolinium (Gd3+) ions co-substituted hydroxyapatite nanoparticles has been developed for X-ray and magnetic resonance imaging. Ag+ and Gd3+ ions were co-substituted into hydroxyapatite at various atomic percentages (Ag:Gd=0.25:0.25, 0.25:0.5, 0.25:0.75) using microwave accelerated wet chemical synthesis. Pure as well as Ag+ and Gd3+ ions substituted hydroxyapatite samples were also synthesized for comparison. All samples were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy etc., and found to be monophasic, nanocrystalline w.. Read More»
  

  Abstract PDF