Journal of Clinical and Experimental Ophthalmology
Open Access
ISSN: 2155-9570
+44 1223 790975
ISSN: 2155-9570
+44 1223 790975
Seiichiro Hayashi
Hongo 3-1-3, Bunkyo-ku, Tokyo
Japan
Research Article
Pathological Study of Secondary Glaucoma due to Congenital Syphilis-A New Theory of Vasculitis in the Schlemm's Canal
Author(s): Seiichiro Hayashi, Teruhiko Hamanaka and Tamiko TakemuraSeiichiro Hayashi, Teruhiko Hamanaka and Tamiko Takemura
Aims: To investigate histopathological changes in trabeculectomy (TLE) specimens in patients with secondary glaucoma due to congenital syphilis.
Methods: Eleven eyes of 8 patients were used. The areas of TLE observed by gonioscopy were photographed before the surgery. Each of 13 TLE specimens (two eyes received TLE twice) were processed for light and transmission electron microscopy.
Results: There was no inflammation in the anterior chamber at the time of TLE in any eyes. Gonioscopy showed a mixture of normal, thick pigmentation and peripheral anterior synechia. A variety of histological changes in the angle was observed among the samples or even in the same samples: normal (7 eyes) or occluded (8 eyes) Schlemm’s canal with (7 eyes) or without (4 eyes) inflammatory cells. These various changes were also observed i.. View More»