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Soleimany Ferizhandy Ali
Soleimany Ferizhandy Ali
Iranian Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine,
Tehran
West Indies
Publications
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Research Article
Influence of Different Methods Preparation on Platelet Activation in Stored Platelet Concentrates
Author(s): Soleimany Ferizhandy AliSoleimany Ferizhandy Ali
Background: Platelet concentrates are routinely manufactured from whole blood by differential centrifugation. During this storage period under blood bank conditions, biochemical, structural and functional changes occur, a process that is also known as platelet storage lesion. Their quality was assessed using the following parameters: platelets, leukocytes and erythrocytes counts, pH, CD63, lactate dehydrogenase and Annexin V. Materials and Methods: In this experimental study, 25 platelet concentrates prepared with platelet rich plasma-platelet concentrates, 25 units via buffy coat and apheresis-derived platelet methods. The percentages of Annexin V, CD63 expression, lactatedehydrogenase, platelet, leukocytes counts and pH were evaluated. Results: During storage for up to 5 days, no significant pH, difference was observ.. View More»
DOI: 10.4172/2155-9864.1000279