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Staal FJT | OMICS International
ISSN: 2155-9899

Journal of Clinical & Cellular Immunology
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Staal FJT

L3-35, L3-35, Leiden University Medical Center, P.O. Box 9600, 2300 RC/ Leiden
The Netherlands

DNA Barcoding of Human Stem and Progenitor Cells Reveals Differences in Clonal Dynamics of B and T lymphoid Progeny

Proper immune reconstitution after hematopoietic stem cell (HSC) transplantation requires de novo T cell development in the thymus to ensure a broad and diverse T cell receptor (TCR) repertoire. The clonal relationship between HSCs and T lymphocytes has long been unclear, especially for human T cells. Previous work showed severe clonal restriction ... Read More»

Brugman MH and Staal FJT

Commentary: J Clin Cell Immunol 2016, 7: 408

DOI: 10.4172/2155-9899.1000408

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF