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T Macek | OMICS International
ISSN: 2161-0444

Medicinal Chemistry
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T Macek

Czech Republic
Publications

Solid-Phase Synthesis and In Vitro Cytotoxicity of New Peptide Functionalized Cyclencarboxymethylen and L-DOPA Hybrids

The new small peptide functionalized cyclen and DOPA derivatives were synthesized: cyclen-HisHis, cyclen- AspHis, cyclen-GluHis, DOPA-HisHis were prepared. The solid-phase synthesis strategy was used for preparation of new compounds. Synthesized cyclen- and DOPA-oligopeptide hybrid conjugations were purified by HPLC and analyzed using MALDI-TOF MS ... Read More»

L Arabuli, R Jezek, T Macek, P Lovecka, E Nikoleishvili, N Sulashvili and I Maisuradze

Research Article: Med chem (Los Angeles) 2017, 7: 398

DOI: 10.4172/2161-0444.1000487

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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