Translational Medicine
Open Access

Takemi Tanaka

Publications

• Review Article
  E-selectin: Its Role in Cancer and Potential as a Biomarker
  Author(s): Aman P. Mann and Takemi TanakaAman P. Mann and Takemi Tanaka
  
  The involvement of E-selectin in cancer has long been recognized based on histopathological studies, and the important role of E-selectin in cancer progression and metastasis was further reinforced by a number of basic researches. Both the solid state and soluble forms of E-selectin have been tested as a possible biomarker for different cancer types for detection as well as for monitoring. While a number of studies have suggested the potential usefulness of E-selectin as a biomarker, the results from clinical trials are somewhat controversial and it has not been translated into clinical utility. It appears that the use of E-selectin as a single biomarker for diagnosis and prognosis may require more careful evaluation. The utility of E-selectin as a biomarker in conjunction with other biomarkers that are relevant to the biological cascade for E-selectin or are critical for patient prog.. View More»
  

  Abstract PDF

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