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Thomas B Neff | OMICS International
ISSN: 2577-0535

Journal of Cancer Clinical Trials
Open Access

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Thomas B Neff

USA
Publications

FG-3019, A Human Monoclonal Antibody to Connective Tissue Growth Factor, Combined with Chemotherapy in Patients with Locally Advanced or Metastatic Pancreatic Ductal Adenocarcinoma

Purpose: Connective tissue growth factor (CTGF) is overexpressed in pancreatic ductal adenocarcinoma (PDAC) and facilitates local desmoplasia, tumor progression and metastasis in animal models. This study evaluated safety and initial efficacy of the anti-CTGF antibody FG-3019 in combination with gemcitabine and erlotinib in patients with previously... Read More»

Vincent J Picozzi, J. Marc Pipas, Albert C Koong, Amato J Giaccia, Nathan Bahary, Smitha S Krishnamurthi, Charles D Lopez, Peter O’Dwyer, Katharina Modelska, Mairead Carney, James Chou, Ming Zhong, Stefan Hemmerich, Dongxia Li, Ewa Carrier, Seth Porter, Thomas B Neff and Frank H Valone

Research Article: J Cancer Clin Trials 2017, 2:123

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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