Tomoya Sano
Japan
Research Article
Are Dyslipidemia Following Obesity and Hyperglycemia as an Indicator of Diabetes Involved in Dental Caries Development in Zucker Rats?
Author(s): Yasushi Kodama, Kiyokazu Ozaki, Tomoya Sano, Yui Terayama, Taiki Nishimoto, Yoshihiko Taniguchi and Tetsuro MatsuuraYasushi Kodama, Kiyokazu Ozaki, Tomoya Sano, Yui Terayama, Taiki Nishimoto, Yoshihiko Taniguchi and Tetsuro Matsuura
Several studies indicated that both obesity and diabetes are related to dental caries development, but their involvement remains unclear. Thus, we investigated the effect of obesity and diabetes on dental caries development using obese Zucker fatty (ZF) rats, obese Zucker diabetic fatty (ZDF) rats, and Zucker lean (Lean) rats as controls.
Eight ZF, 6 ZDF, and 7 Lean male rats were studied. We macroscopically examined the mandibular and maxillary molars and evaluated soft X-ray photographs for caries development. From each group, 5 mandibles and maxillae were examined histologically.
The ZF rats’ average body weight was more than twice that of the other 2 groups, but the ZDF and Lean rats had comparable body weights. The average triglyceride and total cholesterol levels were elevated in the ZF and ZDF rats, but the ZF rats’ average triglyceride and total.. View More»
